TTURC
2: Tobacco Dependence, Treatment and Outcomes
(2005-2009)
Research
Project 2
Natural History of Smoking and Quitting: Long-term Outcomes
This research involves the transdisciplinary integration of information on the health
and psychosocial outcomes of a quit attempt. This information should provide data that will help:
- Reduce
late relapse.
- Motivate more smokers to quit.
- Motivate clinicians to
treat smokers more effectively.
- Provide a basis for preventive interventions
to avoid negative impacts of quitting.
Researchers are studying about 360 successful
quitters and 540 continuing smokers from Project 1, using the same assessment
tools as in the first project. The goal is to learn about the fates of
quitters and non-quitters in terms of mental health, quality of life,
alcohol intake, cardiovascular effects and more—to answer the
question: What happens to quitters after they quit?
Participants who received intensive in-person assessments before the quit date will have selected measures repeated at one,
two and three years post-quit attempt. We hypothesize that successful
cessation will be associated with arrest of atherosclerosis progression,
reduction in alcohol intake, enhanced quality-of-life and reduced psychiatric
symptoms/diagnoses. We also expect that a portion of quitters will experience
negative outcomes after quitting, especially those gaining substantial
weight. These outcomes may include decreased quality of life, decreased
exercise and hyperlipidemia. Finally, the long follow-up interval will
allow us to identify precipitants of late relapse: i.e., relapse occurring
after one year of abstinence.
Research
Project 1: Pharmacotherapies: Efficacy, Mechanisms and Algorithms
Research
Project 3: Pharmacotherapies: Effectiveness in Primary Care Systems
Research
Project 4: Healthcare Costs and Utilization of Smoking and Quitting
More
Information
Understanding and Preventing
Relapse, TTURC 1 (1999-2004)
Tobacco
Dependence: Treatment and Outcomes, TTURC 2 (2004-2009)
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