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TTURC 2: Tobacco Dependence, Treatment and Outcomes
(2005-2009)

Research Project 3
Pharmacotherapies: Effectiveness in Primary Care Systems

This project addresses the effectiveness of cessation medications offered in real-world primary care settings. It also assesses patients’ willingness to participate in cessation treatment, and evaluates treatment recruitment and delivery strategies. Primary care patients who present for a regular outpatient visit will be recruited by medical assistants to participate in a free smoking-cessation program. They'll be randomly assigned to the same five active pharmacotherapies evaluated in Project 1.

Interested patients who pass medical screening pick up their medications at clinic pharmacies and receive proactive telephone counseling from the Wisconsin Tobacco Quit Line.

Researchers assess individual differences to validate treatment algorithms developed in Project 1. They'll also estimate the costs of incorporating tobacco-dependence treatment into primary care.

Smoking status is followed for one year, and health care utilization is tracked for three years as part of Project 4. Thus, Project 3 will reveal the relative effectiveness of five different pharmacotherapies in real-world primary care settings, the utility of an algorithm for assigning pharmacotherapies based on individual differences, and the cost-effectiveness and success of this treatment recruitment and delivery strategy.

Research Project 1: Pharmacotherapies: Efficacy, Mechanisms and Algorithms

Research Project 2: Natural History of Smoking and Quitting: Long-term Outcomes

Research Project 4: Healthcare Costs and Utilization of Smoking and Quitting

More Information
Understanding and Preventing Relapse, TTURC 1 (1999-2004)

Tobacco Dependence: Treatment and Outcomes, TTURC 2 (2004-2009)


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